ETIOLOGY : Prostate cancer mainly develops within the glandular Component of the prostate gland. Cells mutate from genetic Transformation and gradually become malignant with uncontrollable growth at which point they can spread beyond the prostate firs to the Surrounding areas then distantly to the lymph nodes, bones and even other organs lf left untreated or unsuccessfully treated patient with suffer from multiple organ failure, pain, debilitation and eventually death.
DIGNOSIS : Majority of early stage prostate cancer will not cause any Recognizable symptom. Lt can only be detected by rising PSA ( Prostatic Specific Antigen ) with or without abnormal or suspicious digital rectal finding with a definitive histologic proof of presence of cancer by prostate biopsy guided by transrectal ultrasound and more recently with the help of MRI ( Magnetic Resonance Imaging ) as well
TREATMENT RECOMMENDATION : Will depend on several factors Namely histologic grading of cancer level of PSA at presentation Digital rectal finding and whether or not the cancer remains confined within the prostate
Treatment approaches for organ-confined prostate cancer :
>There are currently mainly 3 modalities to choose from :
>Radical Prostatectomy :
>Retropubic Radical Prostatectomy
>Robotic Assisted Laparoscopic Radical Prostatectomy
>Transperinal Radical Prostatectomy ( Rarely done )
> External Beam Radiation
> lntensity Modulated Radiotherapy ( IMRT )
> lmage Guided IMRT
> Cyberknife
> Proton Beam
>Brachytherapy
> Low-Dose-Rate Brachytherapy : l 125 , Pd 103 , Cs 131
> High-Dose-Rate Brechytherapy : lr 192
There are differences in pros and cons for each of the above named treatment modalities . To Appreciate the right treatment approach for particular patient it is important to be able to obtain appropriate information from the right sources with open mind
LOW-DOSE-RATE Brachytherapy
At Chularat 3 international Hospital we have Dr. Viroon Donavanik,MD,FACR who has been practicing Radiation Oncology for 40 years and who is highly specialized in low – dose – rate Brachytherapy both in the united states and in Thailand.
Such procedure has yielded 97% cancer-free rete at 5 years for Stage l procedure cancer in Dr. Donavaanik ‘ s own record and between 85- 93% for all stage ll cases ( ll A and ll B ) with the understanding that in all stage ll B and some stses ll A patients may also require or will be weeks along with androgen deprivation therapy (hormone treatment) as well which is standard treatment recommendation worldwide.
The benefit of low-dose-rate Brachytherapy :
>A single 1 - 2 hours procedure under general anesthesia
>Immediate recovery
>Cure rate is as high as any other treatment modalities if not higher
( in Dr.Donavanik´s experience )
>Sexual function preservation is the best
>Very remote possibility of urinary incontinence
Consultation with Dr. Donavanik can be made at Chularat 3 international Hospital
Call center : 1609 or 091-770-6639
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